Match the following genetic disorders (A to E) to the clinical descrip-tion (5-7):
A. Klinefelter syndrome (XXY)
B. XYY male
C. Turner syndrome (XO)
D. Fragile X syndrome
E. XXX syndrome
5- An institutionalized male juvenile delinquent appears at first glance to be normal. Upon closer examination he is noted to have severe nodulocystic acne, mild pectus excavatum, large teeth, prominent glabella, and relatively long face and fingers. His fam¬ily reports that he has poor fine motor skills (such as handwriting), an explosive temper, and a low normal IQ.
6- A tall, thin 14-year-old boy has yet to have any signs of puberty. His mother reports that he was delayed in his speech develop¬ment and always has done less well in school than his siblings. She reports that he is very shy, and teachers report his activity to be immature. Physical examination reveals signs of breast devel¬opment, and long limbs with a decreased upper to lower segment ratio. His testes and phallus are small, and he has no evidence of pubertal development.
7- A 15-year-old with primary amenorrhea is noted to be well below the 5th percentile for height for her age. Her vital signs are sig¬nificant for hypertension. On examination, she has a low poste¬rior hairline, prominent and low-set ears, and excessive nuchal skin.